© 2021 Center for Infectious Diseases, Nara Medical University

研究業績

2022年

  1. Ogawa Y, Ote H, Arai T, Kazama R, Kimura K, Nagata T, Kumasawa J, Kohno M, Kohata H, Nishida K, Gohma I, Kasahara K. Corynebacterium pseudodiphtheriticum as a Pathogen in Bacterial Co-Infection in COVID-19 Patients on Mechanical Ventilation. Jpn J Infect Dis. 2022 Mar 24;75(2):202-204. doi: 10.7883/yoken.JJID.2021.481. Epub 2021 Aug 31. PMID: 34470958.
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  2. Onishi T, Shimonishi N, Takeyama M, Furukawa S, Ogiwara K, Nakajima Y, Kasahara K, Nishio K, Yoshimoto K, Inoue S, Kawaguchi M, Fukushima H, Saito Y, Yoshiji H, Muro S, Tsuruya K, Okada S, Sugie K, Kawaguchi R, Nishikubo T, Yamazaki M, Oda Y, Kawabe T, Onishi K, Nishio T, Nogami K. The balance of comprehensive coagulation and fibrinolytic potential is disrupted in patients with moderate to severe COVID-19. Int J Hematol. 2022 Jun;115(6):826-837. doi: 10.1007/s12185-022-03308-w. Epub 2022 Feb 16. PMID: 35171446; PMCID: PMC8852977.
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  3. Chang B, Tamura K, Fujikura H, Watanabe H, Tanabe Y, Kuronuma K, Fujita J, Oshima K, Maruyama T, Abe S, Kasahara K, Nishi J, Kubota T, Kinjo Y, Serizawa Y, Shimbashi R, Fukusumi M, Shimada T, Sunagawa T, Suzuki M, Oishi K; Adult IPD Study Group. Pneumococcal meningitis in adults in 2014-2018 after introduction of pediatric 13-valent pneumococcal conjugate vaccine in Japan. Sci Rep. 2022 Feb 23;12(1):3066. doi: 10.1038/s41598-022-06950-w. PMID: 35197497; PMCID: PMC8866494.
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  4. Suzuki Y, Nakano R, Nakano A, Tasaki H, Asada T, Horiuchi S, Saito K, Watanabe M, Nomura Y, Kitagawa D, Lee ST, Ui K, Koizumi A, Nishihara Y, Sekine T, Sakata R, Ogawa M, Ohnishi M, Tsuruya K, Kasahara K, Yano H. Comamonas thiooxydans Expressing a Plasmid-Encoded IMP-1 Carbapenemase Isolated From Continuous Ambulatory Peritoneal Dialysis of an Inpatient in Japan. Front Microbiol. 2022 Feb 21;13:808993. doi: 10.3389/fmicb.2022.808993. PMID: 35265058; PMCID: PMC8899508.
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  5. Ohno Y, Aoyagi K, Arakita K, Doi Y, Kondo M, Banno S, Kasahara K, Ogawa T, Kato H, Hase R, Kashizaki F, Nishi K, Kamio T, Mitamura K, Ikeda N, Nakagawa A, Fujisawa Y, Taniguchi A, Ikeda H, Hattori H, Murayama K, Toyama H. Newly developed artificial intelligence algorithm for COVID-19 pneumonia: utility of quantitative CT texture analysis for prediction of favipiravir treatment effect. Jpn J Radiol. 2022 Aug;40(8):800-813. doi: 10.1007/s11604-022-01270-5. Epub 2022 Apr 9. PMID: 35396667; PMCID: PMC8993669.
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  6. Oka K, Matsumoto A, Tetsuka N, Morioka H, Iguchi M, Ishiguro N, Nagamori T, Takahashi S, Saito N, Tokuda K, Igari H, Fujikura Y, Kato H, Kanai S, Kusama F, Iwasaki H, Furuhashi K, Baba H, Nagao M, Nakanishi M, Kasahara K, Kakeya H, Chikumi H, Ohge H, Azuma M, Tauchi H, Shimono N, Hamada Y, Takajo I, Nakata H, Kawamura H, Fujita J, Yagi T; Japan Infection Prevention and Control Conference for National and Public University Hospitals. Clinical characteristics and treatment outcomes of carbapenem-resistant Enterobacterales infections in Japan. J Glob Antimicrob Resist. 2022 Jun;29:247-252. doi: 10.1016/j.jgar.2022.04.004. Epub 2022 Apr 13. PMID: 35429667.
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  7. Tamura K, Chang B, Shimbashi R, Watanabe H, Tanabe Y, Kuronuma K, Oshima K, Maruyama T, Fujita J, Abe S, Kasahara K, Nishi J, Kubota T, Kinjo Y, Fujikura H, Fukusumi M, Shimada T, Sunagawa T, Suzuki M, Yamamoto Y, Oishi K; Adult IPD Study Group. Dynamic changes in clinical characteristics and serotype distribution of invasive pneumococcal disease among adults in Japan after introduction of the pediatric 13-valent pneumococcal conjugate vaccine in 2013-2019. Vaccine. 2022 May 26;40(24):3338-3344. doi: 10.1016/j.vaccine.2022.04.062. Epub 2022 Apr 28. PMID: 35489986.
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  8. Nishioka H, Onishi T, Kitano T, Takeyama M, Imakita N, Kasahara K, Kawaguchi R, Masaki JA, Nogami K. A survey of healthcare workers' recommendations about human papillomavirus vaccination. Clin Exp Vaccine Res. 2022 May;11(2):149-154. doi: 10.7774/cevr.2022.11.2.149. Epub 2022 May 31. PMID: 35799873; PMCID: PMC9200650.
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  9. Chang B, Morita M, Nariai A, Kasahara K, Kakutani A, Ogawa M, Ohnishi M, Oishi K. Invasive Streptococcus oralis Expressing Serotype 3 Pneumococcal Capsule, Japan. Emerg Infect Dis. 2022 Aug;28(8):1720-1722. doi: 10.3201/eid2808.212176. PMID: 35876607; PMCID: PMC9328907.
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  10. Kanayama A, Tsuchihashi Y, Otomi Y, Enomoto H, Arima Y, Takahashi T, Kobayashi Y, Kaku K, Sunagawa T, Suzuki M; COVID-19 discharge summary database (CDSD) group. Association of severe COVID-19 outcomes with radiological scoring and cardiomegaly: findings from the COVID-19 inpatients database, Japan. Jpn J Radiol. 2022 Jul 26:1–10. doi: 10.1007/s11604-022-01300-2. Epub ahead of print. PMID: 35881259; PMCID: PMC9315080.
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  11. Hachisu Y, Tamura K, Murakami K, Fujita J, Watanabe H, Tanabe Y, Kuronuma K, Kubota T, Oshima K, Maruyama T, Kasahara K, Nishi J, Abe S, Nakamura M, Kubota M, Hirai S, Ishioka T, Ikenoue C, Fukusumi M, Sunagawa T, Suzuki M, Akeda Y, Oishi K; Adult IHD Study Group. Invasive Haemophilus influenzae disease among adults in Japan during 2014-2018. Infection. 2022 Jul 28. doi: 10.1007/s15010-022-01885-w. Epub ahead of print. PMID: 35902511.
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  12. Kitabatake M, Ouji-Sageshima N, Sonobe S, Furukawa R, Konda M, Hara A, Aoki H, Suzuki Y, Imakita N, Nakano A, Fujita Y, Shichino S, Nakano R, Ueha S, Kasahara K, Muro S, Yano H, Matsushima K, Ito T. Transition of antibody titers after the SARS-CoV-2 mRNA vaccine in Japanese healthcare workers. Jpn J Infect Dis. 2022 Aug 31. doi: 10.7883/yoken.JJID.2022.041. Epub ahead of print. PMID: 36047181.
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  13. Fujikura H, Imakita N, Ogawa T, Kasahara K. Graft-duodenal fistula as a cause of recurrent bacteremia. Infection. 2022 Sep 15. doi: 10.1007/s15010-022-01920-w. Epub ahead of print. PMID: 36107380.
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2021年

  1. Hayakawa M, Takano K, Kayashima M, Kasahara K, Fukushima H, Matsumoto M. Management of a COVID-19 Patient during ECMO: Paying Attention to Acquired von Willebrand Syndrome. J Atheroscler Thromb. 2021 Apr 1;28(4):396-401. PMID: 33116032.
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  2. Yoshihara S, Yamana H, Akahane M, Kishimoto M, Nishioka Y, Noda T, Matsui H, Fushimi K, Yasunaga H, Kasahara K, Imamura T. Association between prophylactic antibiotic use for transarterial chemoembolization and occurrence of liver abscess: a retrospective cohort study. Clin Microbiol Infect. 2021 Jan 16:S1198-743X(21)00041-0. PMID: 33465502.
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  3. Hirai N, Nishioka Y, Sekine T, Nishihara Y, Okuda N, Nishimura T, Fujikura H, Imakita N, Fukumori T, Ogawa T, Hishiya N, Suzuki Y, Nakano R, Yano H, Sato M, Maeda K, Imamura T, Kasahara K. Factors associated with viral clearance periods from patients with COVID-19: A retrospective observational cohort study. J Infect Chemother. 2021 Jun;27(6):864-868. PMID: 33642249.
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  4. Chang B, Kinjo Y, Morita M, Tamura K, Watanabe H, Tanabe Y, Kuronuma K, Fujita J, Oshima K, Maruyama T, Abe S, Kasahara K, Nishi J, Kubota T, Ohnishi M, Suga S, Oishi K. Distribution and Variation of Serotypes and Pneumococcal Surface Protein A Clades of Streptococcus pneumoniae Strains Isolated From Adult Patients With Invasive Pneumococcal Disease in Japan. Front Cell Infect Microbiol. 2021 Mar 19;11:617573. PMID: 33869075.
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  5. Nakanishi Y, Kasahara K, Koizumi A, Tokutani J, Yoshihara S, Mikasa K, Imamura T. Evaluation of Nosocomial Infection Control Measures to Minimize the Risk of Aspergillus Dispersion During Major Demolition Work: A Case Study of a Japanese University Hospital. HERD. 2021 May 7:19375867211009979. PMID: 33957793.
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  6. Ogawa T, Hirai N, Imakita N, Fujikura H, Kajita A, Imai Y, Onishi T, Takeyama M, Kasahara K. Travelers' vaccines and their adverse events in Nara, Japan. Open Med (Wars). 2021 Jun 30;16(1):978-985. PMID: 34250252.
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  7. Kuwahara M, Yurugi S, Ando J, Takeuchi M, Miyata R, Harada M, Masuda Y, Kanagawa S, Yoneda T, Fukumori T, Ogawa T, Nakamura-Uchiyama F, Kasahara K. A case of cryptococcal necrotizing fasciitis and immune reconstitution inflammatory syndrome in a renal transplantation recipient. Int J Surg Case Rep
    . 2021 Jul 16;85:106199. PMID: 34280874
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  8. Ueda N, Imada M, Kato Y, Okuda N, Nakaue K, Horita S, Kinoshita S, Kasahara K, Kirita T. Bevacizumab-associated implant presence-triggered osteonecrosis: A case report and literature review. J Oral Implantol. 2021 Jul 26. doi: 10.1563/aaid-joi-D-21-00155. Epub ahead of print. PMID: 34313770.
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  9. Ando J, Miyata R, Harada M, Takeuchi M, Kasahara K, Yoshimoto Y, Koyama F, Kuwahara M. A Ventral Hernia-repair-related Mycobacterium mageritense Mesh Infection Treated with NPWT without Mesh Removal. Plast Reconstr Surg Glob Open. 2021 Sep 7;9(9):e3799. doi: 10.1097/GOX.0000000000003799. PMID: 34513541; PMCID: PMC8423399.
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  10. Furukawa R, Kitabatake M, Ouji-Sageshima N, Suzuki Y, Nakano A, Matsumura Y, Nakano R, Kasahara K, Kubo K, Kayano SI, Yano H, Ito T. Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model. Sci Rep. 2021 Dec 8;11(1):23695. doi: 10.1038/s41598-021-03149-3. PMID: 34880383; PMCID: PMC8654961.
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2020年

  1. Hishiya N, Uno K, Amano M, Asada K, Masui K, Ishida Y, Suzuki Y, Hirai N, Nakano A, Nakano R, Kasahara K, Yano H, Mikasa K. Filifactor alocis brain abscess identified by 16S ribosomal RNA gene sequencing: A case report. J Infect Chemother. 2020 Feb;26(2):305-307. PMID: 31711830.
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  2. Hayakawa K, Nakano R, Hase R, Shimatani M, Kato H, Hasumi J, Doi A, Sekiya N, Nei T, Okinaka K, Kasahara K, Kurai H, Nagashima M, Miyoshi-Akiyama T, Kakuta R, Yano H, Ohmagari N. Comparison between IMP carbapenemase-producing Enterobacteriaceae and non-carbapenemase-producing Enterobacteriaceae: a multicentre prospective study of the clinical and molecular epidemiology of carbapenem-resistant Enterobacteriaceae. J Antimicrob Chemother. 2020 Mar 1;75(3):697-708. PMID: 31789374 .
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  3. Ogawa T, Inoue T, Kasahara K, Konishi M, Mikasa K. Impact of vaccination on measles, mumps, and rubella antibody titers in Japanese healthcare workers: An observational study. PLoS One. 2020 Mar 24;15(3):e0230329. PMID: 32208432.
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  4. Yanagihara K, Mikasa K, Kasahara K, et al. Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of japanese society of chemotherapy, the japanese association for infectious diseases, and the japanese society for clinical microbiology in 2016: General view of the pathogens’ antibacterial susceptibility. J Infect Chemother. 2020 Sep;26(9):873-881. PMID: 32565151.
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  5. Hirai N, Kasahara K, Yoshihara S, Nishimura T, Ogawa Y, Ogawa T, Hishiya N, Suzuki Y, Yano H, Yoshikawa M.Spinal epidural abscess caused by non-typhoidal Salmonella: A case report and literature review. J Infect Chemother. 2020 Oct;26(10):1073-1077. PMID: 32591325 .
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  6. Hirai N, Kasahara K, Yoshihara S, Nishimura T, Omori K, Ogawa Y, Ogawa T, Hishiya N, Suzuki Y, Yano H, Yoshikawa M, Mikasa K.Necessity to screen and treat latent tuberculosis before ruxolitinib treatment-Ruxolitinib-associated disseminated tuberculosis: A case report and literature review.IDCases. 2020 Jun 26;21:e00892. PMID: 32642438.
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  7. Ogawa T, Fukumori T, Nishihara Y, Sekine T, Okuda N, Nishimura T, Fujikura H, Hirai N, Imakita N, Kasahara K.Another false-positive problem for a SARS-CoV-2 antigen test in Japan. J Clin Virol. 2020 Oct;131:104612. PMID: 32871543.
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  8. Shimbashi R, Suzuki M, Chang B, Watanabe H, Tanabe Y, Kuronuma K, Oshima K, Maruyama T, Takeda H, Kasahara K, Fujita J, Nishi J, Kubota T, Tanaka-Taya K, Matsui T, Sunagawa T, Oishi K; Adult IPD Study Group. Effectiveness of 23-Valent Pneumococcal Polysaccharide Vaccine against Invasive Pneumococcal Disease in Adults, Japan, 2013-2017. Emerg Infect Dis. 2020 Oct;26(10):2378-2386. PMID: 3294672.
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  9. Yano H, Nakano R, Suzuki Y, Nakano A, Kasahara K, Hosoi H. Inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by gaseous ozone treatment. J Hosp Infect. 2020 Oct 10:S0195-6701(20)30464-3. PMID: 33049366.
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  10. Hirai N, Kasahara K, Nakano R, Ogawa Y, Suzuki Y, Ogawa M, Hishiya N, Nakano A, Ichimura S, Yano H, Yoshikawa M. Clinical characteristics and molecular epidemiology of invasive Streptococcus agalactiae infections between 2007 and 2016 in Nara, Japan. PLoS One. 2020 Oct 19;15(10):e0240590. PMID: 33075112.
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  11. Yonekawa S, Mizuno T, Nakano R, Nakano A, Suzuki Y, Asada T, Ishii A, Kakuta N, Tsubaki K, Mizuno S, Ogawa M, Yano H, Kasahara K, Mikasa K. Molecular and epidemiological characteristics of carbapenemase-producing Klebsiella pneumoniae clinical isolates in Japan. mSphere. 2020 Oct 21;5(5):e00490-20. PMID: 33087515.
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  12. Ogawa Y, Nishida K, Gohma I, Kasahara K, Yano H. Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel. BMC Res Notes. 2020 Nov 7;13(1):511. PMID: 33160412.
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2019年

  1. Imakita N, Kitabatake M, Ouji-Sageshima N, Hara A, Morita-Takemura S, Kasahara K, Matsukawa A, Wanaka A, Mikasa K, Ito T. Abrogated Caveolin-1 expression via histone modification enzyme Setdb2 regulates brain edema in a mouse model of influenza-associated encephalopathy.Sci Rep. 2019 Jan 22;9(1):284. PMID: 30670717.
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  2. Shimbashi R, Chang B, Tanabe Y, Takeda H, Watanabe H, Kubota T, Kasahara K, Oshima K, Nishi J, Maruyama T, Kuronuma K, Fujita J, Ikuse T, Kinjo Y, Suzuki M, Kerdsin A, Shimada T, Fukusumi M, Tanaka-Taya K, Matsui T, Sunagawa T, Ohnishi M, Oishi K; Adult IPD Study Group.Epidemiological and clinical features of invasive pneumococcal disease caused by serotype 12F in adults, Japan. PLoS One. 2019 Feb 21;14(2):e0212418. PMID: 30789928.
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  3. Kato H, Senoh M, Honda H, Fukuda T, Tagashira Y, Horiuchi H, Chiba H, Suzuki D, Hosokawa N, Kitazono H, Norisue Y, Kume H, Mori N, Morikawa H, Kashiwagura S, Higuchi A, Kato H, Nakamura M, Ishiguro S, Morita S, Ishikawa H, Watanabe T, Kojima K, Yokomaku I, Bando T, Toimoto K, Moriya K, Kasahara K, Kitada S, Ogawa J, Saito H, Tominaga H, Shimizu Y, Masumoto F, Tadera K, Yoshida J, Kikuchi T, Yoshikawa I, Watanabe T, Honda M, Yokote K, Toyokawa T, Miyazato H, Nakama M, Mahe C, Reske K, Olsen MA, Dubberke ER. Clostridioides (Clostridium) difficile infection burden in Japan: A multicenter prospective study.Anaerobe. 2019 Dec;60:102011. PMID: : 30872073.
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  4. Ueda T, Takesue Y, Tokimatsu I, Miyazaki T, Nakada-Motokawa N, Nagao M, Nakajima K, Mikamo H, Yamagishi Y, Kasahara K, Yoshihara S, Ukimura A, Yoshida K, Yoshinaga N, Izumi M, Kakeya H, Yamada K, Kawamura H, Endou K, Yamanaka K, Yoshioka M, Amino K, Ikeuchi H, Uchino M, Miyazaki Y. The incidence of endophthalmitis or macular involvement and the necessity of a routine ophthalmic examination in patients with candidemia.PLoS One. 2019 May 23;14(5):e0216956. PMID: 31120928.
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  5. Yamada A, Kasahara K, Ogawa Y, Samejima K, Eriguchi M, Yano H, Mikasa K, Tsuruya K. Peritonitis due to Moraxella osloensis: A case report and literature review.J Infect Chemother. 2019 Dec;25(12):1050-1052. PMID: 31196771.
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  6. Yanagihara K, Mikasa K, Kasahara K, Koizumi A, et al. Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for clinical microbiology in 2014: General view of the pathogens' antibacterial susceptibility.J Infect Chemother. 2019 Sep;25(9):657-668. doi: 10.1016/j.jiac.2019.05.006. Epub 2019 Jun 10.PMID: 31196772.
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  7. Uno K, Hishiya N, Matsuda M, Kai Y, Amano M, Nakamura A, Tohjyo T, Kawaguchi T, Nakano R, Yano H, Kasahara K, Mikasa K. Case of endobronchial metastasis from breast cancer accompanied with Cunninghamella bertholletiae tracheobronchial mycetoma.J Infect Chemother. 2019 Dec;25(12):1065-1069. PMID: 31227382.
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  8. Ogawa Y, Kasahara K, Asada T, Yoshihara S, Hirai N, Furukawa R, Nishimura T, Ohmori K, Nakano R, Yano H, Mikasa K. Scrotal ulcer due to community-acquired methicillin-resistant Staphylococcus aureus USA300 clone in an HIV-positive man who has sex with men in Japan: a case report. Int J STD AIDS. 2019 Oct;30(12):1229-1231. PMID: 31558138.
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  9. Senoh M, Kato H, Honda H, Fukuda T, Tagashira Y, Horiuchi H, Chiba H, Suzuki D, Hosokawa N, Kitazono H, Norisue Y, Kume H, Mori N, Morikawa H, Kashiwagura S, Higuchi A, Kato H, Nakamura M, Ishiguro S, Morita S, Ishikawa H, Watanabe T, Kojima K, Yokomaku I, Bando T, Toimoto K, Moriya K, Kasahara K, Kitada S, Ogawa J, Saito H, Tominaga H, Shimizu Y, Masumoto F, Tadera K, Yoshida J, Kikuchi T, Yoshikawa I, Watanabe T, Honda M, Yokote K, Toyokawa T, Miyazato H, Nakama M, Mahe C, Reske K, Olsen MA, Dubberke ER. Performance of laboratory tests for detection for Clostridioides difficile: A multicenter prospective study in Japan.Anaerobe. 2019 Dec;60:102107. PMID: 31647977.
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  10. Harada S, Aoki K, Yamamoto S, Ishii Y, Sekiya N, Kurai H, Furukawa K, Doi A, Tochitani K, Kubo K, Yamaguchi Y, Narita M, Kamiyama S, Suzuki J, Fukuchi T, Gu Y, Okinaka K, Shiiki S, Hayakawa K, Tachikawa N, Kasahara K, Nakamura T, Yokota K, Komatsu M, Takamiya M, Tateda K, Doi Y. Clinical and Molecular Characteristics of Klebsiella pneumoniae Isolates Causing Bloodstream Infections in Japan: Occurrence of Hypervirulent Infections in Health Care. J Clin Microbiol. 2019 Oct 23;57(11):e01206-19. PMID: 31434721.
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  11. Ogawa Y, Nakano R, Kasahara K, Mizuno T, Hirai N, Nakano A, Suzuki Y, Kakuta N, Masui T, Yano H, Mikasa K. Comparison of the inoculum size effects of antibiotics on IMP-6 β-lactamase-producing Enterobacteriaceae co-harboring plasmid-mediated quinolone resistance genes. PLoS One. 2019 Nov 13;14(11):e0225210. PMID: 31721789.
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